THE GENE FOR THE ALPHA-1-SUBUNIT OF THE SKELETAL-MUSCLE DIHYDROPYRIDINE-SENSITIVE CALCIUM-CHANNEL (CCHL1A3) MAPS TO MOUSE CHROMOSOME-1

被引：15
|
作者：
CHIN, H
KRALL, M
KIM, HL
KOZAK, CA
MOCK, B
机构：
[1] NIAID,MOLEC MICROBIOL LAB,BETHESDA,MD 20892
[2] NCI,GENET LAB,BETHESDA,MD 20892
来源：
GENOMICS | 1992年 / 14卷 / 04期
关键词：
D O I：
10.1016/S0888-7543(05)80134-X
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Cchl1a3 encodes the dihydropyridine-sensitive calcium channel α1 subunit isoform predominantly expressed in skeletal muscle. mdg (muscular dysgenesis) has previously been implicated as a mutant allele of this gene. Hybridization of a rat brain cDNA probe for Cchl1a3 to Southern blots of DNAs from a panel of Chinese hamster × mouse somatic cell hybrids suggested that this gene maps to mouse Chromosome 1. Analysis of the progeny of an inbred strain cross-positioned Cchl1a3 1.3 cM proximal to the Pep-3 locus on Chr 1. © 1992 Academic Press, Inc. All rights reserved.
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页码：1089 / 1091
页数：3
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