MEASUREMENT ON MUCOCILIARY CLEARANCE IN THE UPPER AIRWAYS OF BEAGLE DOGS

被引：3

作者：

FERRON, GA ^{[1
]}

ERBE, F ^{[1
]}

FURST, G ^{[1
]}

HEILMANN, P ^{[1
]}

KREYLING, WG ^{[1
]}

MOLLENSTADT, S ^{[1
]}

NEUNER, M ^{[1
]}

SCHUMANN, G ^{[1
]}

机构：

[1] GESELL STRAHLEN & UMWELTFORSCH MBH, INST STRAHLENBIOL, W-8042 NEUHERBERG, GERMANY

来源：

JOURNAL OF AEROSOL SCIENCE | 1991年 / 22卷

关键词：

DEPOSITION AND CLEARANCE; PARTICLE INHALATION;

D O I：

10.1016/S0021-8502(05)80236-8

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

A standardized method is described to determine the mucociliary clearance of monodisperse insoluble In-111 labelled polystyrene particles in the upper airways of anesthetized dogs. 60-mu-l of particle suspension are dispersed through a nozzle at the tip of a fiberoptic bronchoscope. The particle transport in the trachea is followed by the radioactivity movement using a gamma camera. The results for 13 dogs indicated an intraindividual subject reproducibility of about 25%.

引用

页码：S867 / S870

页数：4

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