IN-SITU SURFACE-SELECTIVE MODIFICATION OF UNIFORM SIZE MACROPOROUS POLYMER PARTICLES WITH TEMPERATURE-RESPONSIVE POLY-N-ISOPROPYLACRYLAMIDE

被引：61

作者：

HOSOYA, K ^{[1
]}

SAWADA, E ^{[1
]}

KIMATA, K ^{[1
]}

ARAKI, T ^{[1
]}

TANAKA, N ^{[1
]}

FRECHET, JMJ ^{[1
]}

机构：

[1] CORNELL UNIV,BAKER LAB,DEPT CHEM,ITHACA,NY 14853

来源：

MACROMOLECULES | 1994年 / 27卷 / 14期

关键词：

D O I：

10.1021/ma00092a042

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

A new in situ surface-selective modification procedure for the incorporation of temperature-responsive poly-N-isopropylacrylamide (poly-NIPAM) into porous polymer beads has been developed. This procedure allows the incorporation of the poly-NIPAM either on the internal surface of the macroporous beads or on their external surface selectively. The process involves the addition of NIPAM monomer and a water-soluble radical initiator to a polymerizing mixture consisting of uniformly sized monomer and porogen particles prepared by a two-step swelling and polymerization method. NIPAM polymerizes in the aqueous phase but soon precipitates out because the upper critical solution temperature of poly-NIPAM is exceeded. If cyclohexanol is used as the porogen for the monodispersed beads, poly-NIPAM dissolves in the cyclohexanol and is able to penetrate all pores of the beads where it becomes grafted at their surface. With toluene as the porogen, poly-NIPAM being insoluble in the porogen cannot penetrate the pores but only becomes grafted onto the external surface of the beads. The characteristics of the poly-NIPAM-modified particles were confirmed by a simple chromatographic process.

引用

页码：3973 / 3976

页数：4

共 8 条

[1]

FRECHET JMJ, 1994, Patent No. 5306561

[2] PHASE-TRANSITION OF AQUEOUS-SOLUTIONS OF POLY(N-ISOPROPYLACRYLAMIDE) AND POLY(N-ISOPROPYLMETHACRYLAMIDE) [J].