A MILD METHOD FOR CONVERSION OF EPOXIDES INTO ALPHA-CHLORO KETONES

被引：10

作者：

RAINA, S ^{[1
]}

BHUNIYA, D ^{[1
]}

SINGH, VK ^{[1
]}

机构：

[1] INDIAN INST TECHNOL,DEPT CHEM,KANPUR 208016,UTTAR PRADESH,INDIA

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 40期

关键词：

D O I：

10.1016/S0040-4039(00)61116-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Epoxides on treatment with DMSO, oxalyl chloride, and 10 mole % of methanol in the presence of triethylamine at -60-degrees-C are converted to alpha-chloro ketones in high yield.

引用

页码：6021 / 6022

页数：2

共 8 条

[1]

ASCOLI R, 1981, TETRAHEDRON LETT, V21, P4521

[2] CATALYTIC ENANTIOSELECTIVE SYNTHESIS OF (3S)-2,3-OXIDOSQUALENE [J].

COREY, EJ ;

YI, KY ;

MATSUDA, SPT .

TETRAHEDRON LETTERS, 1992, 33 (17) :2319-2322

[3] A STABLE AND EASILY PREPARED CATALYST FOR THE ENANTIOSELECTIVE REDUCTION OF KETONES - APPLICATIONS TO MULTISTEP SYNTHESES [J].

COREY, EJ ;

BAKSHI, RK ;

SHIBATA, S ;

CHEN, CP ;

SINGH, VK .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (25) :7925-7926

[4] FERRIC-CHLORIDE IN ETHER - CONVENIENT REAGENT FOR CONVERSION OF EPOXIDES INTO CHLOROHYDRINS [J].

KAGAN, J ;

FIRTH, BE ;

SHIH, NY ;

BOYAJIAN, CG .

JOURNAL OF ORGANIC CHEMISTRY, 1977, 42 (02) :343-344

[5]

MANCUSO AJ, 1981, SYNTHESIS-STUTTGART, P165

[6] D2H-BISHOMOHEXAPRISMANE (GARUDANE) - DESIGN OF THE FACE-TO-FACE 2+2 DIMER OF NORBORNADIENE [J].

MEHTA, G ;

PADMA, S .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (23) :7230-7232

[7]

OLAH GA, 1979, TETRAHEDRON LETT, P3653

[8]

SINGH VK, 1992, SYNTHESIS

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