SYNTHESIS AND INVITRO ANTIBACTERIAL PROPERTIES OF 2-(3-BROMO-5-ISOXAZOLYLIDENEAMINO-OXY)ACETAMIDO-BETA-LACTAM DERIVATIVES

被引：0

作者：

SALA, A ^{[1
]}

CHIARINO, D ^{[1
]}

NAPOLETANO, M ^{[1
]}

ALBINI, E ^{[1
]}

CARENZI, A ^{[1
]}

机构：

[1] ZAMBON RES LABS,I-20091 BRESSO,ITALY

来源：

FARMACO | 1991年 / 46卷 / 7-8期

关键词：

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The synthesis of new 2-(3-bromo-5-isoxazolylideneaminoxy)acetic acids and their condensation derivatives with suitable beta-lactam nuclei is reported. Their antibacterial properties have been tested in vitro. An interesting activity against Gram-positive bacteria including beta-lactamase-producing microorganisms was found among the cephalosporanic acid derivatives.

引用

页码：887 / 897

页数：11

共 4 条

[1] 1,3-DIPOLAR CYCLOADDITION SYNTHESIS OF 3-BROMO-5-SUBSTITUTED ISOXAZOLES, USEFUL INTERMEDIATES FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE COMPOUNDS [J].