Psoriatic arthritis

被引：0

作者：

Resch-Passini, Johannes ^{[1
]}

Spellitz, Peter ^{[1
]}

机构：

[1] Rheuma Zentrum Wien Oberlaa, Kurbadstr 14, A-1100 Vienna, Austria

来源：

JOURNAL FUR MINERALSTOFFWECHSEL & MUSKULOSKELETTALE ERKRANKUNGEN | 2018年 / 25卷 / 02期

关键词：

Psoriatic arthritis; EULAR recommendations; GRAPPA recommendations; Interleukin-12/23; inhibitors; Interleukin-17; Pathogenesis; Enthesitis; Diagnostic criteria;

D O I：

10.1007/s41970-018-0036-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Psoriatic arthritis presents a heterogeneous clinical picture and constitutes a great diagnostic and therapeutic challenge in daily practice. Enthesitis seems to play a central role in this inflammatory autoimmune disorder. The European League Against Rheumatism (EULAR) recommends a treat-to-target approach in terms of consistent treatment monitoring and adjustment at defined intervals. Gradually, administration of nonsteroidal anti-rheumatics should be followed by treatment with conventional synthetic and biological disease-modifying anti-rheumatic drugs (csDMARDs and bDMARDs) such as TNF-alpha-blockers, interleukin-17, and interleukin-12/23 inhibitors. However, the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) recommends an individual therapeutic approach depending on the affected area.

引用

页码：60 / 66

页数：7

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