Malignant melanoma of the clivus is a rare entity, for which there is little evidence-based literature for guiding clinicians to understand the importance of disease staging via noninvasive imaging strategy. This report highlights the case of a 55-year-old lady with histopathologically confirmed melanocytic melanoma of the clivus-postoperative status, with multiple skeletal metastasis, demonstrated on 2-deoxy-2-[18F] fluoro-D-glucose positron emission tomography/computed tomography (18F-FDG PET/CT scan). The experience gained with this patient demonstrates the feasibility and usefulness of this noninvasive application in accurate staging and hence, correct decision making regarding further treatment.