Aggregation Of Thrombocytes In Patients With Arterial Hypertension With Type 2 Diabetes Mellitus

In modern society, there is still a high prevalence of a combination of arterial hypertension and type 2 diabetes. The great danger of this combination of diseases is associated with the risk of developing against their background frequent thromboses, the mechanisms of which have not been studied sufficiently. The aim is to evaluate the aggregation capacity of platelets in arterial hypertension and type 2 diabetes mellitus. We examined 42 patients of the second adult age (mean age 49.3 +/- 2.9 years) with arterial hypertension of 1-2 degrees, risk 4 with diabetes mellitus type 2. The control group consisted of 26 clinically healthy people of the same age. All examined persons gave written informed consent to participate in the study. Biochemical, hematological and statistical methods of investigation were used. The high incidence of thrombosis in various locations in hypertension in type 2 diabetes is closely related to the development of platelet hyperaggregation. At the heart of its development is the weakening of antioxidant protection of the plasma with activation of the processes of lipid peroxidation, which is very often the case when a combination of arterial hypertension with type 2 diabetes mellitus. It was found that people with arterial hypertension and type 2 diabetes mellitus have an obvious weakening of platelet disaggregation with an increase in their aggregation ability. As a result, patients receive a sharply increased risk of thrombosis of any location, which can lead to disability and death.