SYNTHESES OF BENZOMORPHAN AND RELATED COMPOUNDS .I. SYNTHESIS OF N-SUBSTITUTED-1,2,3,4,5,6-HEXAHYDRO-8-HYDROXY-2,6-METHANO-6,11-DIMETHYL-3 BENZAZOCINE [STUDIES ON SYNTHESES OF HETEROCYCLIC COMPOUNDS .282.]

被引:36
作者
KAMETANI, T
KIGASAWA, K
HIIRAGI, M
HAYASAKA, T
WAGATSUM.N
WAKISAKA, K
机构
[1] Pharmaceutical Institute, School of Medicine, Tohoku University and Research Laboratories, Grelan Pharamaceutical Co, Ltd., Sendai
关键词
D O I
10.1002/jhet.5570060108
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A modified synthesis of pentazocine, l,2,3,4,5,6‐hexahydro‐8‐hydroxy‐2,6‐methano‐6, H‐dimethyl‐3‐(3‐methyl‐2‐butenyl)‐3‐benzazocine (III), has been achieved and catalytic hydro‐genation has been found to be effective for the debenzylation of quaternary ammonium salts. Copyright © 1969 Journal of Heterocyclic Chemistry
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页码:43 / &
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