1,2,3-TRIAZOLE[4,5-D]PYRIDAZINES .1. ANALOGS OF PROSTAGLANDIN SYNTHESIS INHIBITORS

被引：0

作者：

BIAGI, G

FERRETTI, M

GIORGI, I

LIVI, O

SCARTONI, V

LUCACCHINI, A

机构：

[1] FAC FARM PISA,IST CHIM FARMACEUT & TOSSICOL,VIA BONANNO 6,I-56100 PISA,ITALY

[2] FAC FARM PISA,IST POLICATTEDRA DISCIPLINE BIOL,I-56100 PISA,ITALY

来源：

FARMACO | 1993年 / 48卷 / 08期

关键词：

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

This paper reports the preparation of new triazolepyridazine derivatives bearing in the 1 position an acidic substituent, on the basis of a working hypothesis relating these compounds to 1,2,3-triazole derivatives, effective in vitro inhibitors of the prostaglandin synthesis. The tested compounds were lacking of biological activity.

引用

页码：1159 / 1165

页数：7

共 28 条

[1]

ALDOUS DL, 1963, ARZNEIMITTEL-FORSCH, V13, P878

[2]

ANDERSEN L, 1989, CHEM SCRIPTA, V29, P45

[3]

BERTHO A, 1929, J PRACT CHEM, V119, P189

[4]

BIAGI G, 1985, FARMACO-ED SCI, V40, P73

[5]

BIAGI G, 1985, EUR J MED CHEM, V20, P267

[6]

BIAGI G, 1988, FARMACO, V43, P597

[7]

BIAGI G, 1990, FARMACO, V45, P1181

[8]

BIAGI G, 1992, IL FARMACO, V47, P335

[9] SYNTHESIS AND BIOLOGICAL EVALUATION OF CERTAIN 4-ALKYLAMINO AND 4-ARYLALKYLAMINO DERIVATIVES OF THE IMIDAZO[4,5-D]PYRIDAZINE AND V-TRIAZOLO[4,5-D]PYRIDAZINE RING-SYSTEMS [J].

CHEN, SF ;

PANZICA, RP ;

DEXTER, DL ;

WANGCHU, MY ;

CALABRESI, P .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1982, 19 (02) :285-288

[10]

DASETTIMO A, 1979, FARMACO-ED SCI, V34, P371

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