VIBRIO-MIMICUS WITH MULTIPLE TOXIN TYPES ISOLATED FROM HUMAN AND ENVIRONMENTAL SOURCES

被引：23

作者：

RAMAMURTHY, T

ALBERT, MJ

HUQ, A

COLWELL, RR

TAKEDA, Y

TAKEDA, T

SHIMADA, T

MANDAL, BK

NAIR, GB

机构：

[1] NATL INST CHOLERA & ENTER DIS, Kolkata 700010, W BENGAL, INDIA

[2] INT CTR DIARRHOEAL DIS RES, DHAKA 1000, BANGLADESH

[3] UNIV MARYLAND, DEPT MICROBIOL, College Pk, MD 20742 USA

[4] KYOTO UNIV, FAC MED, DEPT MICROBIOL, KYOTO, KYOTO 606, JAPAN

[5] NATL CHILDRENS MED RES CTR, DEPT INFECT DIS RES, TOKYO, TOKYO 154, JAPAN

[6] NATL INST HLTH, BACTERIOL LAB 1, SHINJUKU KU, TOKYO, TOKYO 162, JAPAN

[7] UNIV MANCHESTER, MONSALL HOSP, REG DEPT INFECT DIS & TROP MED, MANCHESTER M10 8WR, LANCS, ENGLAND

来源：

JOURNAL OF MEDICAL MICROBIOLOGY | 1994年 / 40卷 / 03期

关键词：

D O I：

10.1099/00222615-40-3-194

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A collection of 13 strains of Vibrio mimicus, including both clinical and environmental isolates from different geographic regions, was examined for various toxins. One strain of environmental origin produced cholera-like toxin (CT) which was completely absorbed with anti-CT immunoglobulin G, five strains produced a haemolysin that crossreacted with the thermostable direct haemolysin of V. parahaemolyticus and DNA from two strains hybridised with a DNA probe specific for the heat-stable enterotoxin of V. cholerae non-Ol. Culture supernates of all strains produced a factor that was cytotoxic to Vero and Chinese hamster ovary cells. In this study, we were able to identify strains of V. mimicus that produced, or had the genetic potential to produce, several toxin types simultaneously. The role of these strains as genetic reservoirs is discussed.

引用

页码：194 / 196

页数：3

共 21 条

[1] PURIFICATION AND CHARACTERIZATION OF A HEAT-STABLE ENTEROTOXIN OF VIBRIO-MIMICUS [J].