CHIRAL SEPARATION BY CAPILLARY ELECTROPHORESIS

被引：191

作者：

KUHN, R

HOFFSTETTERKUHN, S

机构：

[1] Analytical Research and Development, Sandoz Pharma LTD., Basel

[2] Bad Krozingen

来源：

CHROMATOGRAPHIA | 1992年 / 34卷 / 9-10期

关键词：

CAPILLARY ELECTROPHORESIS; CHIRAL SEPARATION; ENANTIOMERIC SEPARATION;

D O I：

10.1007/BF02290245

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

This paper reviews chiral separations by capillary zone electrophoresis and micellar electrokinetic capillary chromatography. The principles of host-guest complexation, ligand exchange and solubilization by optically active micelles are discussed in detail. An overview of practical examples taken from literature is presented. Results from our laboratory are shown to illustrate the potential of these methods. The review concludes by discussing strong and weak points of the techniques together with possible future developments.

引用

页码：505 / 512

页数：8

共 49 条

[1] MOLECULAR RECEPTORS - FUNCTIONALIZED AND CHIRAL MACROCYCLIC POLYETHERS DERIVED FROM TARTARIC ACID [J].