THE INHIBITORY INPUT FROM THE SUBSTANTIA-NIGRA TO THE MEDIODORSAL NUCLEUS NEURONS PROJECTING TO THE PREFRONTAL CORTEX IN THE CAT

被引：21

作者：

MIYAMOTO, Y

JINNAI, K

机构：

[1] SHIGA UNIV MED SCI,DEPT NEUROSURG,OTSU,SHIGA 52021,JAPAN

[2] SHIGA UNIV MED SCI,DEPT PHYSIOL,OTSU,SHIGA 52021,JAPAN

来源：

BRAIN RESEARCH | 1994年 / 649卷 / 1-2期

关键词：

NIGROTHALAMIC PROJECTION; SUBSTANTIA NIGRA; MEDIODORSAL NUCLEUS; PREFRONTAL CORTEX; ELECTROPHYSIOLOGY; CAT;

D O I：

10.1016/0006-8993(94)91079-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The effects of stimulation of the substantia nigra pars reticulata (SNr) on the neurons of the mediodorsal nucleus (MD) projecting to the prefrontal cortex (PF) were studied in cats. The MD neurons projecting to the ventral part of the PF tended to be located in the ventral part of the MD, while those projecting to the dorsal part of the PF in the dorsal part. Spontaneous discharges of 30/57 tested MD neurons were suppressed by SNr stimulation at a latency ranging from 2 to 15 ms. The latency of the suppression corresponded well to that of antidromic responses of SNr neurons elicited by MD stimulation (from 1.4 to 14.0 ms). Intracellular recordings in a few MD neurons showed IPSP by SNr stimulation. The SNr is considered to exert an inhibitory effect on the MD neurons projecting to the PF.

引用

页码：313 / 318

页数：6

共 19 条

[11]

MARKOWITSCH HJ, 1978, EXP BRAIN RES, V32, P335

[12] THE ORGANIZATION OF THE THALAMOCORTICAL CONNECTIONS OF THE MEDIODORSAL THALAMIC NUCLEUS IN THE RAT, RELATED TO THE VENTRAL FOREBRAIN PREFRONTAL CORTEX TOPOGRAPHY [J].