SENSITIVITY ENHANCEMENT FOR CAPILLARY ELECTROPHORESIS

The relative gains achieved by using the different cell geometries and the chemical means discussed above are summarized in Tables II and III. Advantages and disadvantages of the different methods are indicated in terms of applicability, effects on the separation, and manufacturing concerns. Overall detection limits for the different modes are summarized in Table IV. Very low concentration detection limits can be obtained, and we believe they will become more available to the commercial instrument user as the application market develops. (Already two commercial LIF systems are available, and certainly the number and variety of detection configurations will expand.). © 1993, American Chemical Society. All rights reserved.