LIPID-COMPOSITION OF HUMAN MALIGNANT-MELANOMA TUMORS AT VARIOUS LEVELS OF MALIGNANT GROWTH

被引：144
作者：
PORTOUKALIAN, J
ZWINGELSTEIN, G
DORE, JF
机构：
[1] UNIV LYON 1,CNRS,PHYSIOL GEN & COMPAREE LAB,F-69621 VILLEURBANNE,FRANCE
[2] CTR LEON BERARD,INST NATL SANTE & RECH MED FRA 24,IMMUNOL & CANCEROL EXPTL,F-69373 LYON 2,FRANCE
来源：
EUROPEAN JOURNAL OF BIOCHEMISTRY | 1979年 / 94卷 / 01期
关键词：
D O I：
10.1111/j.1432-1033.1979.tb12866.x
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The lipid pattern of thirteen human melanoma tumors from various tissues were investigated. In seven of the tumors, an estimate was given about the proportion of malignant melanocytes to the total cell population, and a reverse correlation was determined between the proportion of malignant cells in these tumors and their neutral lipid content. The phospholipids did not show any modification, nor did the cholesterol in the cancerous tissues. The ganglioside pattern was found to be similar in all analyzed samples, with GM3, GM2 and GD3 as major components, although no correlation was found between the malignant level and the ganglioside content of the tumors. Copyright © 1979, Wiley Blackwell. All rights reserved
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页码：19 / 23
页数：5
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