HEPATITIS-C VIRUS-INFECTION IN PATIENTS WITH HEMATOLOGICAL DISEASES - EVIDENCE FOR THE ASSOCIATION WITH ERYTHROCYTES TRANSFUSION AND LIVER-DISEASE

被引：1
作者：
PIVETTI, S
NOVARINO, A
CALVO, L
MASSARO, AL
BRUNETTO, MR
CALIGARIS, CF
BONINO, F
机构：
[1] MOLINETTE MAURIZIANO HOSP, DIPARTIMENTO SPERIMENTALE GASTROENTEROL, I-10126 TURIN, ITALY
[2] MOLINETTE MAURIZIANO HOSP, DIPARTIMENTO SCI BIOMED & ONCOL UMANA, I-10126 TURIN, ITALY
[3] MOLINETTE MAURIZIANO HOSP, BLOOD BANK, I-10126 TURIN, ITALY
来源：
INTERNATIONAL HEPATOLOGY COMMUNICATIONS | 1995年 / 4卷 / 01期
关键词：
VIRAL HEPATITIS; HEPATITIS C VIRUS; HCV-RNA; ANTI-HCV; HEPATITIS B VIRUS; ANTI-HBC; BLOOD; ERYTHROCYTE; TRANSFUSION;
D O I：
10.1016/0928-4346(95)00205-W
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
We analysed hepatitis C virus risk factors in 131 consecutive patients with haematological malignancies (17.6% anti-HCV positive), 42 with connective tissue diseases (30.9% anti-HCV positive) and 1071 (1.1% anti-HCV positive) new blood donors. Anti-HCV was associated with elevated serum ALT levels (P = 0.0001) and with red cells (P = 0.045), but not with platelets and plasma transfusions. HCV presence in immunocomplexes immunoadhering on the erythrocytes might explain the association between HCV infection and red cell transfusion. However, other risk factors have to be implicated in haematological malignancies to explain the high anti-HCV prevalence in patients who did not receive blood products.
引用
收藏
页码：9 / 15
页数：7
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