CUTANEOUS DRUG REACTIONS IN HIV-INFECTED PATIENTS IN THE HAART ERA

被引:6
作者
Blanes, M. [1 ]
Belinchon, I. [2 ]
Portilla, J. [3 ]
机构
[1] Hosp Marina Baixa, Unidad Dermatol, Av Alcalde Jaume Botella Mayor 7, Alicante 03570, Spain
[2] Univ Alicante, Hosp Gen, Secc Dermatol, Alicante, Spain
[3] Univ Alicante, Hosp Gen, Unidad Enfermedades Infecciosas, Alicante, Spain
来源
ACTAS DERMO-SIFILIOGRAFICAS | 2009年 / 100卷 / 04期
关键词
HAART; HIV; cutaneous drug reactions;
D O I
10.1016/S0001-7310(09)70819-1
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
The introduction of highly active antiretroviral treatment (HAART) in 1996 radically changed the clinical course of human immunodeficiency virus (HIV) infection as it led to a dramatic reduction in mortality in these patients. However, these treatments have their limitations, including adverse effects, therapeutic failure, pharmacokinetic interactions, the development of resistance, and abnormal immune responses. In this article we review the current situation of cutaneous drug reactions in HIV-infected patients.
引用
收藏
页码:253 / 265
页数:13
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共 120 条
  • [11] Adverse cutaneous reactions associated with the newest antiretroviral drugs in patients with human immunodeficiency virus infection
    Borras-Blasco, J.
    Navarro-Ruiz, A.
    Borras, C.
    Castera, E.
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2008, 62 (05) : 879 - 888
  • [12] DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) syndrome associated with nevirapine therapy
    Bourezane, Y
    Salard, D
    Hoen, B
    Vandel, S
    Drobacheff, C
    Laurent, R
    [J]. CLINICAL INFECTIOUS DISEASES, 1998, 27 (05) : 1321 - 1322
  • [13] Explosion of tuberculin-specific Th1-responses induces immune restoration syndrome in tuberculosis and HIV co-infected patients
    Bourgarit, A
    Carcelain, G
    Martinez, V
    Lascoux, C
    Delcey, V
    Gicquel, B
    Vicaut, E
    Lagrange, PH
    Sereni, D
    Autran, B
    [J]. AIDS, 2006, 20 (02) : F1 - F7
  • [14] Paronychia and pyogenic granuloma of the great toes in patients treated with indinavir
    Bouscarat, F
    Bouchard, C
    Bouhour, D
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1998, 338 (24) : 1776 - 1777
  • [15] Alopecia associated with indinavir therapy
    Bouscarat, F
    Prevot, MH
    Matheron, S
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1999, 341 (08) : 618 - 618
  • [16] Atazanavir for the treatment of human immunodeficiency virus infection
    Busti, AJ
    Hall, RG
    Margolis, DM
    [J]. PHARMACOTHERAPY, 2004, 24 (12): : 1732 - 1747
  • [17] Calista D, 2005, EUR J DERMATOL, V15, P97
  • [18] Adverse effects of antiretroviral therapy
    Carr, A
    Cooper, DA
    [J]. LANCET, 2000, 356 (9239) : 1423 - 1430
  • [19] Pathogenesis of HIV-1-protease inhibitor-associated peripheral lipodystrophy, hyperlipidaemia, and insulin resistance
    Carr, A
    Samaras, K
    Chisholm, DJ
    Cooper, DA
    [J]. LANCET, 1998, 351 (9119) : 1881 - 1883
  • [20] Tumid lupus erythematosus occurring following highly active antiretroviral therapy for HIV infection: A manifestation of immune restoration
    Chamberlain, AJ
    Hollowood, K
    Turner, RJ
    Byren, I
    [J]. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2004, 51 (05) : S89 - S93