IN-VITRO ANTIFUNGAL ACTIVITY OF LEAF EXTRACTS OF LEUCAS ASPERA AND LEUCAS ZEYLANICA

被引:9
|
作者
Babu, A. [1 ]
Mohamed, M. Sheik Noor [1 ]
Jaikumar, K. [1 ]
Anand, D. [1 ]
Saravanan, P. [1 ]
机构
[1] Ramakrishna Mission Vivekananda Coll, Dept Bot, Madras 600004, Tamil Nadu, India
来源
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH | 2016年 / 7卷 / 02期
关键词
Leucas aspera; Leucas zeylanica; antifungal; dermatophytes;
D O I
10.13040/IJPSR.0975-8232.7(2).752-56
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The aim of the present study is to probe the antimicrobial activities of methanol leaf extract of Leucas sp. Antifungal susceptibilities of certain clinically isolated dermatophytes to methanol extracts of Leucas aspera and Leucas zeylanica leaves were performed using agar well diffusion method. The result obtained shows that all the extracts expressed remarkable antifungal activity with zone of inhibition ranging from 5 to 10mm. Maximum inhibition zone was recorded with Penicillium sp. (10 mm) while minimum inhibition zone of was recorded for Candida tropicalis (3 mm). From the study it is evident that Leucas aspera and Leucas zeylanica possess potential antidermatophytic activity and further study on these plants may lead to explore novel bioactive compounds.
引用
收藏
页码:752 / 756
页数:5
相关论文
共 50 条
  • [1] Evaluation of The In-Vitro Anthelmintic Activity of Leucas zeylanica Extracts on Earthworms
    Manisekaran, Hemagirri
    Selahuddeen, Muhammad Luqman
    Rahmat, Zaidah
    Abdullah, Faizuan
    Samad, Abdul Fatah A.
    MALAYSIAN APPLIED BIOLOGY, 2023, 52 (04) : 57 - 64
  • [2] Antimicrobial activity of Leucas aspera flowers
    Mangathayaru, K
    Lakshmikant, J
    Sundar, NS
    Swapna, R
    Grace, XF
    Vasantha, J
    FITOTERAPIA, 2005, 76 (7-8) : 752 - 754
  • [3] INVESTIGATION ON REGIONAL VARIATION IN TOTAL PHENOLIC, ALKALOID CONTENT AND IN-VITRO ANTIOXIDANT ACTIVITY OF LEUCAS ASPERA
    Rao, Ganga B.
    Rajeswararao, P.
    Murty, P. Prayaga
    Rao, E. Sambasiva
    Madhukiran, P.
    Rao, T. Mallikarjuna
    Praneeth, V. S. D.
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2011, 2 (10): : 2699 - 2703
  • [4] PHYTOCHEMICAL SCREENING AND ANTIOXIDANT ACTIVITY OF LEUCAS ASPERA
    Das, B. K.
    Das, B.
    Arpita, F. K.
    Morshed, M. A.
    Uddin, A.
    Bhattacherjee, R.
    Hannan, J. M. A.
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2011, 2 (07): : 1746 - 1752
  • [5] Antihyperlipidemic Activity of Leaf Extracts of Leucas aspera Linn. against Dexamethasone-induced Hyperlipidemia in Rats
    Kumar, G. Vijay
    Devanna, N.
    ASIAN JOURNAL OF PHARMACEUTICS, 2016, 10 (03) : S408 - S413
  • [6] Antioxidant and antibacterial activity of different parts of Leucas aspera
    Ai Lan Chew
    Jeyanthi James Antony Jessica
    Sreenivasan Sasidharan
    Asian Pacific Journal of Tropical Biomedicine, 2012, (03) : 176 - 180
  • [7] Identification of phytoconstituents and in-vitro evaluation of the putative anticataractogenic effect of an ethanolic root extract of Leucas aspera
    Sundararajan, Mahalingam
    Thomas, Philip A.
    Babyshalini, Karuppan
    Geraldine, Pitchairaj
    BIOMEDICINE & PHARMACOTHERAPY, 2017, 85 : 87 - 101
  • [8] Larvicidal potential of silver nanoparticles synthesized from Leucas aspera leaf extracts against dengue vector Aedes aegypti
    Suganya, Ganesan
    Karthi, Sengodan
    Shivakumar, Muthugounder S.
    PARASITOLOGY RESEARCH, 2014, 113 (05) : 1673 - 1679
  • [9] GC-MS Analysis and in vitro Cytotoxicity and Antioxidant Studies on Leucas aspera
    Parimaladevi, S. T.
    Raj, C. David
    Sudha, V.
    Brindha, P.
    ASIAN JOURNAL OF CHEMISTRY, 2014, 26 (12) : 3675 - 3678
  • [10] Investigation on Optimized Flavonoid Extraction from Leucas zeylanica and Its Anthelmintic Activity
    Selahuddeen, Muhammad Luqman
    Bouguerra, Marouane
    Hashim, Siti Ernieyanti
    Wahab, Roswanira Abdul
    Samad, Abdul Fatah A.
    Abdullah, Faizuan
    MALAYSIAN JOURNAL OF FUNDAMENTAL AND APPLIED SCIENCES, 2024, 20 (02): : 497 - 513