IMMUNOLOGICAL-TOLERANCE IN HUMAN TRANSPLANTATION - THE POSSIBLE EXISTENCE OF A MATERNAL EFFECT

被引：29

作者：

PANAJOTOPOULOS, N

IANHEZ, LE

NEUMANN, J

SABBAGA, E

KALIL, J

机构：

[1] UNIV SAO PAULO,DIV UROL,RENAL TRANSPLANT UNIT,SAO PAULO,BRAZIL

[2] UNIV SAO PAULO,FAC MED,MED INVEST RHEUMATOL LAB,SAO PAULO,BRAZIL

来源：

TRANSPLANTATION | 1990年 / 50卷 / 03期

关键词：

D O I：

10.1097/00007890-199009000-00016

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We analyzed data from 93 patients who received a kidney graft from their parents; 55 were transplanted with a kidney from their mothers (Mat.) and thirty- eight from their fathers (Pat.) The Pat. group has shown a better graft and patient survival as well as long-term renal function when compared with the Mat. group. This pattern was more evident with time. Long-term graft function assessed by creatinine levels also showed differences between the groups, favoring the Pat. group. The results are interesting since recent reports have claimed a tolerance developed by the individual to noninherited HLA antigens of their mother. © 1990 by Williams and Wilkins.

引用

页码：443 / 445

页数：3

共 7 条

[1]

AMOS DB, 1979, NIH80545 PUBL, P42

[2]

Cicciarelli J, 1988, Clin Transpl, P293

[3] INDUCTION OF B-CELL UNRESPONSIVENESS TO NONINHERITED MATERNAL HLA ANTIGENS DURING FETAL LIFE [J].