Influence of therapy with micronised phenofibrat and symvastatin on rheologic properties of the blood

被引:0
|
作者
Petrova, M. N. [1 ]
机构
[1] MI RGU, Moscow, Russia
来源
YAKUT MEDICAL JOURNAL | 2005年 / 04期
关键词
hyperlipoproteidemy; rheologic properties of the blood; phenofibrat (lipantil); symvastatin (vasilip);
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Aim. To analyse interaction between indices of lipidogram and rheologic properties of the blood (RPB) in various hyperlipoproteidemic (HLP) types for their treatment at early stage. Materials and methods. 50 patients (21 men and 29 women with middle age 51,2 +/- 1,3 and 55,8 +/- 2,4 accordingly) with HLP types IIa, IIb and IV were subjected to comparison of influence of micronised phenofibrat (Lipantil) therapy in daily dose of 20 mg on rheologic properties of the blood (RPB). Conclusion. Both preparations studied had a positive effect upon RPB. Moreover, lipantil made much better the blood viscosity and deformed properties of erythrocytes reducing their aggregation, particularly in HLP type IV. Vasilip took lesser effect on RPB as compared with lipantil.
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页码:11 / 15
页数:5
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