RESISTANCE TO ETHIDIUM-BROMIDE IN ASPERGILLUS-NIDULANS

被引：1
作者：
SCARAZZATTI, ME
BONATELLI, R
AZEVEDO, JL
机构：
[1] Department of Genetics and Evolution, Institute of Biology, University of Campinas, São Paulo
来源：
EXPERIENTIA | 1979年 / 35卷 / 03期
关键词：
D O I：
10.1007/BF01964316
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
A mutant of Aspergillus nidulans resistant to ethidium bromide was isolated and the semi-dominant gene responsible for this resistance was allocated on linkage group II at 17.42±3.05 units of recombination from the wA3 gene. The gene also confers cross-resistance to acriflavin, malachite green and crystal violet. It was also shown that riboflavin is antagonistic to the toxic effect of ethidium bromide, at certain concentrations. The mechanisms which could be responsible for the toxic effect of this drug are discussed and compared with those of acriflavin. The use of the Etb1 gene in genetical analysis through the parasexual cycle is suggested. © 1978 Birkhäuser Verlag.
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页码：307 / 308
页数：2
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