In this article we will analyze the priorities, changes and continuities in relations between the United States and Africa during the Trump Administration, explaining the implications of the political actions of recent years within a broad context that encompasses the historical evolution of US-Africa relations. First of all, we will present an overview of the historical context and the evolution of the complex relationship between the United States and Africa. Secondly, we will examine the relationship during 2017, where there is no formulation of an African policy by the Trump Administration, there are no nominations of senior officials for African affairs, and there is a lack of genuine interest in Africa. Thirdly, we will extend the analysis to 2018, when the United States tries to reset its relationship with Africa, Trump makes key appointments for major Africa posts, and the Administration's Africa policy takes form with focus on security issues and countering China's growing presence and influence. Finally, the article concludes with a number of reflections about the political actions of the Trump Administration regarding Africa.