THE TOTAL SYNTHESIS OF PACLITAXEL BY ASSEMBLY OF THE RING-SYSTEM

被引：0

作者：

NICOLAOU, KC ^{[1
]}

GUY, RK ^{[1
]}

机构：

[1] UNIV CALIF SAN DIEGO, DEPT CHEM, LA JOLLA, CA 92037 USA

来源：

TAXANE ANTICANCER AGENTS: BASIC SCIENCE AND CURRENT STATUS | 1995年 / 583卷

关键词：

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Taxol is an important anticancer agent that is active in a number of cancers including breast and ovarian. The total synthesis of Taxol has been a goal for numerous synthetic groups over the past two decades. Presented herein is the total synthesis of the natural enantiomer of Taxol.

引用

页码：302 / 312

页数：11

共 50 条

[31] SYNTHESIS OF 4-QUINAZOLONE RING-SYSTEM
KREUTZBERGER, A
UZBEK, MU
ARCHIV DER PHARMAZIE UND BERICHTE DER DEUTSCHEN PHARMAZEUTISCHEN GESSELSCHAFT, 1972, 305 (03): : 171 - +
[32] SYNTHETIC STUDIES ON CYATHINS - SYNTHESIS OF THE RING-SYSTEM
WARD, DE
CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1987, 65 (10): : 2380 - 2384
[33] REGIOSELECTIVE SYNTHESIS OF THE KINAMYCIN ABCD RING-SYSTEM
OSULLIVAN, PJ
MORENO, R
MURPHY, WS
TETRAHEDRON LETTERS, 1992, 33 (04) : 535 - 538
[34] SYNTHESIS OF DIOXATRICYCLOHEXADECANE - NEW POLYCYCLIC RING-SYSTEM
GMERNICKAHAFTEK, C
WIENIAWSKI, W
ACTA POLONIAE PHARMACEUTICA, 1975, 32 (02): : 139 - 144
[35] CYCLOHEXANNULATED [5.3.1]PROPELLANES AS PRECURSORS TO THE ABC RING-SYSTEM OF PACLITAXEL (TAXOL(TM))
BANWELL, MG
GABLE, RW
PETERS, SC
PHYLAND, JR
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1995, (13) : 1395 - 1397
[36] TOTAL SYNTHESIS OF TETRACYCLIC TRITERPENES .1. THE (+/-)-5-EPI-EUPHANE RING-SYSTEM
KOLACZKOWSKI, L
REUSCH, W
JOURNAL OF ORGANIC CHEMISTRY, 1985, 50 (24) : 4766 - 4771
[37] SYNTHESIS OF SUBSTITUTED BENZOPHENALENOFURANS - NOVEL PENTACYCLIC RING-SYSTEM
BRENNER, M
BRUSH, C
TETRAHEDRON LETTERS, 1977, (05) : 419 - 422
[38] HETEROATOM CYCLOPENTENE ANNULATION - SYNTHESIS OF GUAIANE RING-SYSTEM
HUDLICKY, T
GOVINDAN, SV
FRAZIER, JO
JOURNAL OF ORGANIC CHEMISTRY, 1985, 50 (21) : 4166 - 4171
[39] SYNTHESIS OF THE ABC RING-SYSTEM OF BREVETOXIN-B
NICOLAOU, KC
DUGGAN, ME
HWANG, CK
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1989, 111 (17) : 6666 - 6675
[40] SYNTHESIS OF THE FG RING-SYSTEM OF BREVETOXIN-B
NICOLAOU, KC
DUGGAN, ME
HWANG, CK
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1989, 111 (17) : 6676 - 6682

← 1 2 3 4 5 →