MELANOCYTE-MARKER-HMB-45 IS REGULARLY EXPRESSED IN ANGIOMYOLIPOMA OF THE KIDNEY

被引：209

作者：

PEA, M ^{[1
]}

BONETTI, F ^{[1
]}

ZAMBONI, G ^{[1
]}

MARTIGNONI, G ^{[1
]}

RIVA, M ^{[1
]}

COLOMBARI, R ^{[1
]}

MOMBELLO, A ^{[1
]}

BONZANINI, M ^{[1
]}

SCARPA, A ^{[1
]}

GHIMENTON, C ^{[1
]}

DONATI, LF ^{[1
]}

机构：

[1] UNIV VERONA,INST PATHOL ANAT,I-37100 VERONA,ITALY

来源：

PATHOLOGY | 1991年 / 23卷 / 03期

关键词：

ANGIOMYOLIPOMA; HMB-45; IMMUNOHISTOCHEMISTRY; LYMPH NODE INVOLVEMENT;

D O I：

10.3109/00313029109063563

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

HMB-45 (melanocytic cell-specific monoclonal antibody) immunoreactivity was investigated in 10 cases of angiomyolipoma (AML) (1 with massive regional lymph node involvement) of the kidney and detected in all of them. No HMB-45 immunoreactivity was found in other tumors of the region which can occassionally be confused with AML, such as renal cell carcinoma, Wilms' tumor, and retroperitoneal sarcoma (leiomyosarcoma and liposarcoma). These findings indicate that HMB-45 is not a melanocyte-restricted marker and suggest that its expression might be useful in distinguishing AML from other tumors of the kidney and retroperitoneum.

引用

页码：185 / 188

页数：4

共 17 条

[1] BREAST-CARCINOMA WITH POSITIVE RESULTS FOR MELANOMA MARKER (HMB-45) - HMB-45 IMMUNOREACTIVITY IN NORMAL AND NEOPLASTIC BREAST [J].