A CASE FOR CYTOKINES AS EFFECTOR MOLECULES IN THE RESOLUTION OF VIRUS-INFECTION

被引：203
作者：
RAMSAY, AJ
RUBY, J
RAMSHAW, IA
机构：
来源：
IMMUNOLOGY TODAY | 1993年 / 14卷 / 04期
关键词：
D O I：
10.1016/0167-5699(93)90277-R
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Some cytokines are known to have potent antiviral activity in vitro, and recent work shows that severely immunodeficient mice, which lack conventional effector T cells, can still recover from virus infection provided these factors are present at sites of virus replication. Here Alistair Ramsay, Janet Ruby and Ian Ramshaw discuss these findings and raise fundamental questions concerning the physiological role of cytotoxic T cells in the resolution of virus infection.
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页码：155 / 157
页数：3
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