DIRECTED EVOLUTION OF NOVEL BIOSYNTHETIC PATHWAYS - GROWTH OF AN ESCHERICHIA-COLI PROLINE AUXOTROPH ON DELTA(1)-PYRROLINE-2-CARBOXYLIC ACID

被引：3

作者：

SUTHERLAND, JD ^{[1
]}

WILSON, EJ ^{[1
]}

WRIGHT, MC ^{[1
]}

机构：

[1] UNIV OXFORD,CTR MOLEC SCI,OXFORD OX1 3QY,ENGLAND

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1993年 / 3卷 / 06期

关键词：

D O I：

10.1016/S0960-894X(00)80311-X

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A directed approach to the evolution of novel biosynthetic pathways is exemplified by the selection of plasmids which enhance the growth of an Escherichia coli proline auxotroph on an unnatural precursor, DELTA1-pyrroline-2-carboxylic acid 2.

引用

页码：1185 / 1188

页数：4

共 19 条

[1] REDUCTION OF DELTA(1)-PYRROLINE-2-CARBOXYLIC ACID TO PROLINE BY AN ESCHERICHIA-COLI PROLINE AUXOTROPH
LEWIS, ML
MARTIN, SL
ROWE, CJ
SUTHERLAND, JD
WILSON, EJ
WRIGHT, MC
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1993, 3 (06) : 1189 - 1192
[2] REDUCTION OF DELTA(1)-PYRROLINE-2-CARBOXYLIC ACID TO PROLINE IN ESCHERICHIA-COLI - LACK OF INVOLVEMENT OF GLUTAMATE-DEHYDROGENASE AND DELTA(1)-PYRROLINE-5-CARBOXYLATE REDUCTASE
LEWIS, ML
MARTIN, SL
ROWE, CJ
SUTHERLAND, JD
WILSON, EJ
WRIGHT, MC
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1993, 3 (06) : 1197 - 1202
[3] DIRECTED EVOLUTION OF NOVEL BIOSYNTHETIC PATHWAYS - CONSTRUCTION OF A RANDOMLY MUTATED GENE LIBRARY IN AN ESCHERICHIA-COLI PROLINE AUXOTROPH AND SELECTION FOR GROWTH ON POTENTIAL PROLINE PRECURSORS
SUTHERLAND, JD
WILSON, EJ
WRIGHT, MC
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1994, 4 (21) : 2551 - 2554
[4] DIRECTED EVOLUTION OF NOVEL BIOSYNTHETIC PATHWAYS - OVEREXPRESSION OF LEUCINE AMINOPEPTIDASE ALLOWS AN ESCHERICHIA-COLI PROLINE AUXOTROPH TO GROW FASTER ON PROLINAMIDE
LITTLE, AJ
SUTHERLAND, JD
WILSON, EJ
WOODCOLLINS, DAJ
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1994, 4 (21) : 2555 - 2558
[5] THE INTERCONVERSION OF GLUTAMIC ACID AND PROLINE .1. THE FORMATION OF DELTA-1-PYRROLINE-5-CARBOXYLIC ACID FROM GLUTAMIC ACID IN ESCHERICHIA-COLI
STRECKER, HJ
JOURNAL OF BIOLOGICAL CHEMISTRY, 1957, 225 (02) : 825 - 834
[6] EFFECT OF L-AZETIDINE 2-CARBOXYLIC ACID ON GROWTH AND PROLINE METABOLISM IN ESCHERICHIA-COLI
GRANT, MM
BROWN, AS
CORWIN, LM
TROXLER, RF
FRANZBLAU, C
BIOCHIMICA ET BIOPHYSICA ACTA, 1975, 404 (02) : 180 - 187
[7] DIRECTED EVOLUTION OF BIOSYNTHETIC PATHWAYS - RECRUITMENT OF CYSTEINE THIOETHERS FOR CONSTRUCTING THE CELL-WALL OF ESCHERICHIA-COLI
RICHAUD, C
MENGINLECREULX, D
POCHET, S
JOHNSON, EJ
COHEN, GN
MARLIERE, P
JOURNAL OF BIOLOGICAL CHEMISTRY, 1993, 268 (36) : 26827 - 26835
[8] THE EFFECT OF PH ON THE SOLUTION STRUCTURE OF DELTA(1)-PYRROLINE-2-CARBOXYLIC ACID AS REVEALED BY NMR AND ELECTROSPRAY MASS-SPECTROSCOPY
LEWIS, ML
ROWE, CJ
SEWALD, N
SUTHERLAND, JD
WILSON, EJ
WRIGHT, MC
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1993, 3 (06) : 1193 - 1196
[9] INTERCONVERSION OF GLUTAMIC ACID AND PROLINE .2. PREPARATION AND PROPERTIES OF DELTA-1-PYRROLINE-5-CARBOXYLIC ACID
STRECKER, HJ
JOURNAL OF BIOLOGICAL CHEMISTRY, 1960, 235 (07) : 2045 - 2050
[10] δ1-Pyrroline-5-carboxylic acid formed by proline dehydrogenase from the Bacillus subtilis ssp natto expressed in Escherichia coli as a precursor for 2-acetyl-1-pyrroline
Huang, Tzou-Chi
Huang, Yi-Wen
Hung, Hui-Ju
Ho, Chi-Tang
Wu, Mei-Li
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2007, 55 (13) : 5097 - 5102

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