DETERMINATION OF ALLERGEN-SPECIFIC IGE AND IGG ANTIBODIES IN PATIENTS SENSITIZED TO HOUSE-DUST MITES (DERMATOPHAGOIDES-PTERONYSSINUS)

45 patients, hypersensitive to house-dust mites, were examined by the method of skin tests to D. pteronyssinus allergen. Besides, in their blood sera the levels of allergen-specific IgE antibodies were determined in the radioallergosorbent test and allergen-specific IgG antibodies, in the enzyme immunoassay. These tests revealed that in 91 % of the patients the results of skin tests were positive, in 68 % an elevated level of specific IgE antibodies and in 93 % of the patients an elevated level of specific IgG antibodies were detected. All patients showed the positive result in one of the above-mentioned tests. The largest group of the patients (55 %) included persons showing the positive result of the skin test and having elevated levels of allergen-specific IgG and IgE antibodies. Thus, in cases of hypersensitivity to house-dust mites the levels of allergen-specific IgG and IgE antibodies in the patients' blood sera should be determined.