Sulphating 3-acetate Betulin with Chlorosulfonic Acid in Dioxane and Dimethyl Formamide

被引：0

作者：

Levdansky, Vladimir A. ^{[1
,2
]}

Levdansky, Alexandr V. ^{[1
]}

Kuznetsov, Boris N. ^{[1
,2
]}

机构：

[1] RAS, SB, Inst Chem & Chem Technol, 50-24 Akademgorodok, Krasnoyarsk 660036, Russia

[2] Siberian Fed Univ, Krasnoyarsk 660041, Russia

来源：

JOURNAL OF SIBERIAN FEDERAL UNIVERSITY-CHEMISTRY | 2012年 / 5卷 / 03期

关键词：

betulin; betilin 3,28-diacetate; 1,4-dioxane; N; N-dimethylformamide; sulfation; chlorosulfonic acid; SO3-dioxane complex; SO3-dimethylformamide complex; betilin; 3-acetate-28-sulfate; 3-acetate;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

It was established, that the reaction of sulfation of betulin 3-acetate by an chlorosulfonic acid in dioxane or dimethylformamide proceeded in homogeneous medium at temperature 30-40 degrees C. It was shown that for full etherification of betilin 3-acetate to betulin 3-acetate-28-sulfate 1,5-2,5 hours were necessary. Betilin 3-acetate-28-sulfate have received in the form of natrium salt. The structure of betulin 3-acetate-28-sulfate was confirmed by methods of IR and NMR C-13 spectroscopy.

引用

页码：274 / 280

页数：7

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