GAS CHROMATOGRAPHY OF TRIMETHYLSILYL DERIVATIVES OF IODOTYROSINES AND IODOTHYRONINES

被引：29
作者：
ALEXANDER, NM
SCHEIG, R
机构：
[1] Department of Biochemistry, Yale University School of Medicine, New Haven
[2] Department of Medicine, Yale University School of Medicine, New Haven
来源：
ANALYTICAL BIOCHEMISTRY | 1968年 / 22卷 / 02期
关键词：
D O I：
10.1016/0003-2697(68)90306-0
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Gas chromatographic analysis of the trimethylsilyl derivatives of the iodotyrosines, iodothyronines, tyrosine, and thyronine is described. The silylated derivatives can be synthesized within 5 min at 50° using N,O-bis (trimethylsilyl) acetamide and are readily resolved within 30 min by temperature-programmed gas chromatography. Possible biological applications of this separation technique are discussed. © 1968.
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页码：187 / +
页数：1
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