Reactions of nucleophilic addition of alcohols to (-)-alpha-santonin

被引：0

作者：

Merkhatuly, N. ^{[1
]}

Balmagambetova, L. T. ^{[2
]}

Smolenkov, U. U. ^{[1
]}

Iskanderov, A. N. ^{[1
]}

Omarova, A. T. ^{[1
]}

机构：

[1] Karaganda State Univ, Karaganda, Kazakhstan

[2] Karaganda Econ Univ Kazpotrebsoyuza, Karaganda, Kazakhstan

来源：

BULLETIN OF THE UNIVERSITY OF KARAGANDA-CHEMISTRY | 2010年 / 60期

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Reactions of nucleophilic additions of methanol to the natural sesquiterpenoid gamma-lactone (-)-alpha-santonine in the conditions of acid and alkaline catalysis were studied. It was stated that reactions basically proceed on a carbonyl group of the lactone cycle of santonine with reesterification products formation. In this case there is initiated specific prototropic allylic rearrangement with participation of cross-conjugated cyclodienic system and oxy-group of an intermediate hydroxy-ester and leads to formation of practical valuable evdesmanic oxo-esters with high yields. The structure of the compounds synthesized was established on the base of IR, NMR H-1-spectra.

引用

页码：51 / 54

页数：4