ENANTIOCONTROLLED TOTAL SYNTHESES OF (-)-PHYSOVENINE AND (-)-PHYSOSTIGMINE

被引：78
|
作者：
TAKANO, S
MORIYA, M
OGASAWARA, K
机构：
[1] Pharmaceutical Institute, Tohoku University, Aobayama
来源：
JOURNAL OF ORGANIC CHEMISTRY | 1991年 / 56卷 / 21期
关键词：
D O I：
10.1021/jo00021a006
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Enantiocontrolled total syntheses of the Calabar bean alkaloid (-)-physovenine (1) and (-)-physostigmine (2) have been achieved in a concise manner starting from the optically active tricyclic enone 3 employing a Fischer indolization reaction under nonacidic conditions as the key step.
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收藏
页码：5982 / 5984
页数：3
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