GLUTAMIC-ACID DECARBOXYLASE (GAD)-IMMUNOREACTIVE STRUCTURES IN THE ADULT HUMAN LATERAL GENICULATE-NUCLEUS

被引:0
作者
ZINNERFEYERABEND, M [1 ]
BRAAK, E [1 ]
机构
[1] ZENTRUM MORPHOL, THEODOR STERN KAI 7, W-6000 FRANKFURT 70, GERMANY
来源
ANATOMY AND EMBRYOLOGY | 1991年 / 183卷 / 02期
关键词
ADULT HUMAN LATERAL GENICULATE NUCLEUS (LGN); GLUTAMIC ACID DECARBOXYLASE; IMMUNOCYTOCHEMISTRY; INTERNEURONS;
D O I
暂无
中图分类号
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号
100101 ;
摘要
The distribution of glutamic acid decarboxylase (GAD)-like immunoreactivity in the lateral geniculate nucleus (LGN) of the human adult was studied in vibratome sections (50-60-mu-m thick) using the avidinbiotin-peroxidase method. The tissue was obtained at autopsy from five individuals without any known neurological disorders. Only few GAD-immunoreactive neurons were present in the layers of the LGN, even less in the interlaminar zones. The numerical density of GAD-immunoreactive neurons and puncta (probably synaptic boutons and/or cross sectioned cell processes) in the magnocellular layers was larger than in the parvocellular layers. Furthermore, no striking differences between the individual parvocellular layers were noted. The immunoreactive somata were polygonal or triangular, occasionally pear-shaped, and ranged in size from 15 to 25-mu-m. They gave off two to four short, thick, straight primary dendrites. A preferred orientation of dendrites was not recognized. After bleaching the chromogen 4-chloro-1-naphthol and staining for lipofuscin pigment granules and basophilic material, 254 unequivocally relocated GAD-immunoreactive nerve cells could be classified as belonging to the lipofuscin pigment granules-containing class of interneurons.
引用
收藏
页码:111 / 117
页数:7
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