PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES OF BLEOMYCIN COMPLEX ANTIBIOTICS

被引：0

作者：

ZENKOVA, VA ^{[1
]}

YURINA, MS ^{[1
]}

LOMAKINA, NN ^{[1
]}

GOLDBERG, LE ^{[1
]}

BAZHANOV, VS ^{[1
]}

KUNRAT, IA ^{[1
]}

机构：

[1] ACAD MED SCI USSR, INST NEW ANTIBIOT, MOSCOW 14, USSR

来源：

ANTIBIOTIKI | 1979年 / 24卷 / 03期

关键词：

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Bleomycins A2, A5, B2 and B4 in the form of hydrochlorides were isolated from a complex preparation of bleomycin. Their physicochemical properties, in vitro biological activity, toxcity and antitumor effect in experiments with mice were studied. Bleomycin A5 had the highest chemotherapeutic effect.

引用

页码：175 / 179

页数：5

共 14 条

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