EVIDENCE FOR THE EXPRESSION OF A GLUCURONIC ACID-CONTAINING EPITOPE IN THE CENTRAL-NERVOUS-SYSTEM OF 2 INSECTS (CALLIPHORA-VICINA, DIPTERA, TENEBRIO-MOLITOR, COLEOPTERA)

被引：6
作者：
BREIDBACH, O
DENNIS, RD
KELLER, M
WIEGANDT, H
机构：
[1] UNIV BONN, INST PHYSIOL CHEM, W-5300 BONN 1, GERMANY
[2] UNIV MARBURG, INST PHYSIOL CHEM 1, W-3550 MARBURG, GERMANY
来源：
NEUROSCIENCE LETTERS | 1990年 / 109卷 / 03期
关键词：
Beetle; Fly; Glycosphingolipid; Metamorphosis; Neuronal development; Plasma membrane;
D O I：
10.1016/0304-3940(90)90005-T
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The monoclonal antibody CAF-I recognises a glucuronic acid-containing epitope present on various acidic glycosphingolipids of Calliphora vicina. Immunohistochemistry was performed on CAF-I-labelled whole-mount preparations of the central nervous system, visualised by peroxidase-conjugated second antibody. A differential, temporal and spatial expression of this epitope in metamorphosing nervous tissue was outlined, that apparently characterises homologous neuronal populations in two phylogenetically distinct holometabolous insects, i.e. Calliphora vicina and Tenebrio molitor. Implications for a functional interpretation of insect glyco(sphingo)lipids in tissue development are discussed. © 1990.
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页码：265 / 270
页数：6
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