DETERMINATION AND STATISTICAL ANALYSES OF NORMAL RANGES FOR 5 SERUM ENZYMES

The normal serum values of creatine phosphokinase, 1,6-diphosphofructoaldolase, lactate dehydrogenase, aspartate aminotransferase and alanine aminotransferase were measured in fifty healthy individuals of both sexes, using optimal spectrophotometric methods. Serum specimens were handled with particular care in accord with findings due to appear in a forthcoming publication. Normal ranges were established for each enzyme in both sexes; and each was examined for skewness, the effects of age, sex, and time of day at venepuncture, and for correlations between pairs of enzymes in each sex. The findings, some of which were unexpected, are discussed. © 1968.