CHIRAL HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY WITH CELLULOSE CARBAMATE-COATED PHASES - INFLUENCE OF SUPPORT SURFACE-CHEMISTRY ON ENANTIOSELECTIVITY

被引：38
作者：
GRIEB, SJ
MATLIN, SA
BELENGUER, AM
RITCHIE, HJ
机构：
[1] UNIV WARWICK,DEPT CHEM,COVENTRY CV4 7AL,W MIDLANDS,ENGLAND
[2] SB PHARMACEUT,TONBRIDGE TN11 9AN,KENT,ENGLAND
[3] SHANDON HPLC,RUNCORN WA7 1PR,CHESHIRE,ENGLAND
来源：
JOURNAL OF CHROMATOGRAPHY A | 1995年 / 697卷 / 1-2期
基金：
英国工程与自然科学研究理事会;
关键词：
D O I：
10.1016/0021-9673(94)00868-A
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The influence of support surface chemistry on the enantioselectivity and column performance of cellulose tris(3,5-dimethylphenyl carbamate)-coated chiral HPLC phases was investigated. Stable coated phases were produced using underivatised, aminopropylated and octadecylated silica as the support media. For many racemates, underivatised silica at a 20% (w/w) loading was found to be the most efficient phase.
引用
收藏
页码：271 / 278
页数：8
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