A HIGH-RESOLUTION GENETIC-MAP OF MOUSE CHROMOSOME-5 ENCOMPASSING THE REELER (RL) LOCUS

被引：17
作者：
BECKERS, MC
BAR, I
HUYNHTHU, T
DERNONCOURT, C
BRUNIALTI, AL
MONTAGUTELLI, X
GUENET, JL
GOFFINET, AM
机构：
[1] FAC UNIV NOTRE DAME PAIX,SCH MED,DEPT PHYSIOL,B-5000 NAMUR,BELGIUM
[2] INST PASTEUR,UNITE GENET MAMMIFERES,F-75024 PARIS 15,FRANCE
来源：
GENOMICS | 1994年 / 23卷 / 03期
关键词：
D O I：
10.1006/geno.1994.1557
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Using interspecific crosses between BALB/c and Mus spretus (SEG) mice, the murine reeler (rl) gene was mapped to the proximal region of chromosome 5 between the hepatocyte growth factor gene (Hgf) and the D5Mit66 microsatellite. The following order was defined: (centromere)-Cch12a/Hgf-D5Mit1-D5Nam1/D5Nam2- rl/D51Mit61-D5Mit72-Xmv45-Htr5a-Peplb D5Nam3-D5Mit66. Estimated distances between reeler and the nearest flanking markers D5Nam1 and D5Mit72 are 1.5 and 1.0 cM, respectively (95% confidence level), suggesting that the region could be physically mapped using a manageable number of YAC clones. (C) 1994 Academic Press, Inc.
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页码：685 / 690
页数：6
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