PRODRUGS AS DRUG DELIVERY SYSTEMS .4. N-MANNICH BASES AS POTENTIAL NOVEL PRODRUGS FOR AMIDES, UREIDES, AMINES, AND OTHER NH-ACIDIC COMPOUNDS

被引：65
作者：
BUNDGAARD, H
JOHANSEN, M
机构：
来源：
JOURNAL OF PHARMACEUTICAL SCIENCES | 1980年 / 69卷 / 01期
关键词：
D O I：
10.1002/jps.2600690112
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：44 / 46
页数：3
相关论文
共 24 条
[1]   EQUILIBRIA AND KINETICS OF N-HYDROXYMETHYLAMINE FORMATION FROM AROMATIC EXOCYCLIC AMINES AND FORMALDEHYDE - EFFECTS OF NUCLEOPHILICITY AND CATALYST STRENGTH UPON MECHANISMS OF CATALYSIS OF CARBINOLAMINE FORMATION [J].
ABRAMS, WR ;
KALLEN, RG .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1976, 98 (24) :7777-7789
[2]   KINETICS AND MECHANISM OF MANNICH BASE DISSOCIATION IN AQUEOUS BUFFERS [J].
BELIKOV, VM ;
BELOKON, YN ;
DOLGAYA, MM ;
MARTINKO.NS .
TETRAHEDRON, 1970, 26 (05) :1199-&
[3]  
BUNDGAARD H, INT J PHARM
[4]  
BUNDGAARD H, 1978, ARCH PHARM CHEMI SCI, V6, P231
[5]  
BUNDGAARD H, 1979, ARCH PHARM OG CHEM, V86, P1
[6]  
BUNDGAARD H, 1979, ARCH PHARM CHEMI SCI, V7, P41
[7]   STERIC EFFECTS .13. COMPOSITION OF STERIC PARAMETER AS A FUNCTION OF ALKYL BRANCHING [J].
CHARTON, M .
JOURNAL OF ORGANIC CHEMISTRY, 1978, 43 (21) :3995-4001
[8]  
ECKSTEIN M, 1966, DISSERT PHARM PHARMA, V18, P131
[9]  
EINHORN A, 1905, J LIEBIGS ANN CHEM, V343, P207
[10]  
EINHORN A, 1908, LIEBIGS ANN CHEM, V361, P113
123