The Prospect of Immunoglobulin Y for Therapy of Canine Parvovirus Infection in Dogs

被引：0
作者：
Suartini, I. Gusti Ayu Agung [1 ]
Sendow, I [2 ]
机构：
[1] Univ Udayana, Lab Biokimia, Fak Kedokteran Hewan, Jl PB Sudirman, Denpasar, Bali, Indonesia
[2] Balai Besar Penelitian Vet, Bogor 16114, Indonesia
来源：
WARTAZOA-BULETIN ILMU PETERNAKAN DAN KESEHATAN HEWAN INDONESIA | 2015年 / 25卷 / 02期
关键词：
Parvovirus; canine; immunotherapy; immunoglobulin Y;
D O I：
10.14334/wartazoa.v25i2.1142
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
Canine parvovirus (CPV) is a highly infectious virus. The virus causes death in dogs worldwide. The mortality rate due to infection of CPV in dog reaches 91%. Prevention of CPV infection in puppies has been done by vaccination which is effectively proven. Protective mechanisms of maternal antibodies contribute to the failure of vaccination. Highly stable characteristics of parvovirus enable the virus still exist in the environment. Various therapies are performed only to suppress the clinical symptoms but can not reduce puppy mortalities. This review discusses CPV alternative therapy and the advantages using immunoglobulin Y (IgY) specific antibodies isolated from chicken egg yolk. Immunoglobulin Y will neutralize the virus, so it can not infect host cells. Intravenous IgY therapy has shown to suppress the spread of CPV infection and prevent death.
引用
收藏
页码：55 / 64
页数：10
相关论文
共 65 条
  • [1] Analysis of canine parvovirus sequences from wolves and dogs isolated in Italy
    Battilani, M
    Scagliarini, A
    Tisato, E
    Turilli, C
    Jacoboni, I
    Casadio, R
    Prosperi, S
    [J]. JOURNAL OF GENERAL VIROLOGY, 2001, 82 : 1555 - 1560
  • [2] Antibodies: An alternative for antibiotics?
    Berghman, LR
    Abi-Ghanem, D
    Waghela, SD
    Ricke, SC
    [J]. POULTRY SCIENCE, 2005, 84 (04) : 660 - 666
  • [3] Immune therapy for infectious diseases at the dawn of the 21st century:: the past, present and future role of antibody therapy, therapeutic vaccination and biological response modifiers
    Buchwald, UK
    Pirofski, L
    [J]. CURRENT PHARMACEUTICAL DESIGN, 2003, 9 (12) : 945 - 968
  • [4] Human haemoclassification by use of specific yolk antibodies obtained after immunisation of chickens against human blood group antigens
    Calzado, EG
    Garrido, RMG
    Schade, R
    [J]. ATLA-ALTERNATIVES TO LABORATORY ANIMALS, 2001, 29 (06): : 717 - 726
  • [5] General applicability of chicken egg yolk antibodies:: the performance of IgY immunoglobulins raised against the hypoxia-inducible factor 1α
    Camenisch, G
    Tini, M
    Chilov, D
    Kvietikova, I
    Srinivas, V
    Caro, J
    Spielmann, P
    Wenger, RH
    Gassmann, M
    [J]. FASEB JOURNAL, 1999, 13 (01) : 81 - 88
  • [6] Chicken antibodies -: A clinical chemistry perspective
    Carlander, D
    Stålberg, J
    Larsson, A
    [J]. UPSALA JOURNAL OF MEDICAL SCIENCES, 1999, 104 (03) : 179 - 189
  • [7] Carlander D., 2002, ACTA U UPSALIENSIS C, V1119, P153
  • [8] Carman PS, 1985, VET MICROBIOL, V8, P423
  • [9] CARMICHAEL LE, 1980, AM J VET RES, V41, P784
  • [10] Evaluation of the antigenic relationships among canine parvovirus type 2 variants
    Cavalli, Alessandra
    Martella, Vito
    Desario, Costantina
    Camero, Michele
    Bellacicco, Anna Lucia
    De Palo, Pasquale
    Decaro, Nicola
    Elia, Gabriella
    Buonavoglia, Canio
    [J]. CLINICAL AND VACCINE IMMUNOLOGY, 2008, 15 (03) : 534 - 539
1234567