EFFECTIVE SALVAGE THERAPY USING ALL-TRANS-RETINOIC ACID FOR RELAPSED AND RESISTANT ACUTE PROMYELOCYTIC LEUKEMIA

被引：3

作者：

LIANG, R ^{[1
]}

CHOW, WS ^{[1
]}

CHIU, E ^{[1
]}

CHAN, TK ^{[1
]}

LIE, A ^{[1
]}

KWONG, YL ^{[1
]}

CHAN, LC ^{[1
]}

机构：

[1] UNIV HONG KONG,QUEEN MARY HOSP,DEPT PATHOL,HONG KONG,HONG KONG

来源：

ANTI-CANCER DRUGS | 1993年 / 4卷 / 03期

关键词：

ACUTE PROMYELOCYTIC LEUKEMIA; ALL-TRANS-RETINOIC ACID;

D O I：

10.1097/00001813-199306000-00008

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

All-trans retinoic acid (ATRA) has been shown to be active against acute promyelocytic leukemia (APL). Six patients with APL, either in relapse or resistant to initial chemotherapy were reinduced with ATRA 100 g/m2/day for 6 weeks. Complete remission was achieved in all six of them. Side effects were seen in two of them. ATRA appears to provide a relatively safe and reliable means to induce a complete remission in patients with refractory or relapsed APL.

引用

页码：339 / 340

页数：2