Effect of weight loss on activity in psoriatic arthritis: A systematic review

被引:11
作者
Almodovar, Raquel [1 ]
Zarco, Pedro [1 ]
Oton, Teresa [2 ]
Carmona, Loreto [2 ]
机构
[1] Hosp Univ Fdn Alcorcon, Madrid, Spain
[2] InMusc, Inst Salud Musculoesquelet, Madrid, Spain
来源
REUMATOLOGIA CLINICA | 2018年 / 14卷 / 04期
关键词
Body mass index; Obesity; Psoriatic arthritis; Weight loss; Diet; Response to treatment;
D O I
10.1016/j.reuma.2017.01.010
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: To evaluate the association between weight loss and changes in disease activity in patients with psoriatic arthritis (PsA). Methods: We performed a systematic review of the literature, with searches in Medline, Embase and Cochrane Central Library from inception until April 2015. Inclusion criteria: 1) randomized controlled trials (RCT); 2) PsA patients; 3) interventions were any intervention aimed at weight control; and 4) a PsA activity-related outcome measure was evaluated. Risks of bias were assessed by the Cochrane Collaboration scale. Results: Of the 215 articles identified, only 2 RCT met the inclusion criteria, 1 in abstract format. Both showed moderate risk of bias. Patients who managed to lose weight by any method had better results in terms of activity and inflammation. The percentage of weight loss correlated moderately with changes in inflammatory outcomes. Conclusion: Weight loss in PsA could be associated with less inflammation; however, the evidence to support this is limited. (C) 2017 Elsevier Espafia, S.L.U. and Sociedad Espafiola de Reumatologia y Colegio Mexicano de Reumatologia. All rights reserved.
引用
收藏
页码:207 / 210
页数:4
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