FORMATION OF RIBOSOME-G FACTOR-GDP COMPLEX IN PRESENCE OF FUSIDIC ACID

被引：136

作者：

BODLEY, JW

ZIEVE, FJ

LIN, L

ZIEVE, ST

机构：

[1] Department of Biochemistry, University of Minnesota Medical School, Radioisotope Service, Minneapolis

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1969年 / 37卷 / 03期

关键词：

D O I：

10.1016/0006-291X(69)90934-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

When ribosomes are incubated with G factor and GTP, a ribosome-G factor-GDP complex is formed. Fusidic acid does not inhibit the formation of this complex; in fact, more complex is isolated in the presence of the antibiotic (10-3 M) than in its absence. No complex containing GTP is detectable in the presence or absence of the antibiotic. © 1969.

引用

页码：437 / &

共 14 条

[1] ON SPECIFICITY OF 2 RIBOSOMAL BINDING SITES - STUDIES WITH TETRACYCLINE [J].

BODLEY, JW ;

ZIEVE, FJ .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1969, 36 (03) :463-&

[2] FORMATION OF A COMPLEX CONTAINING RIBOSOMES TRANSFER FACTOR G AND A GUANOSINE NUCLEOTIDE [J].

BROT, N ;

SPEARS, C ;

WEISSBAC.H .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1969, 34 (06) :843-&

[3]

ERBE RW, 1969, J MOL BIOL, V38, P441

[4] STEPWISE SYNTHESIS OF A TRIPEPTIDE [J].

HAENNI, A ;

LUCASLEN.J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1968, 61 (04) :1363-&

[5] ASSOCIATION OF FUSIDIC ACID SENSITIVITY WITH G FACTOR IN A PROTEIN-SYNTHESIZING SYSTEM [J].

KINOSHITA, T ;

KAWANO, G ;

TANAKA, N .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1968, 33 (05) :769-+

[6] TRANSLOCATION OF MRNA CODONS .I. PREPARATION AND CHARACTERISTICS OF A HOMOGENEOUS ENZYME [J].

LEDER, P ;

SKOGERSON, LE ;

NAU, MM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1969, 62 (02) :454-+

[7] SEPARATION OF 3 MICROBIAL AMINO ACID POLYMERIZATION FACTORS [J].

LUCASLEN.J ;

LIPMANN, F .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1966, 55 (06) :1562-&

[8] INTERRELATIONSHIP BETWEEN GUANOSINE TRIPHOSPHATASE AND AMINO ACID POLYMERIZATION [J].

NISHIZUKA, Y ;

LIPMANN, F .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1966, 116 (1-3) :344-+

[9] COMPARISON OF GUANOSINE TRIPHOSPHATE SPLIT AND POLYPEPTIDE SYNTHESIS WITH A PURIFIED E COLI SYSTEM [J].

NISHIZUKA, Y ;

LIPMANN, F .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1966, 55 (01) :212-+

[10] PROPERTIES OF CRYSTALLINE AMINO ACID POLYMERIZATION FACTORS FROM ESCHERICHIA COLI - BINDING OF G TO RIBOSOMES [J].

PARMEGGIANI, A ;

GOTTSCHALK, EM .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1969, 35 (06) :861-+

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