Effects of Gluten-Free Diet on Immunological Assays in Children with Celiac Disease

被引：0

作者：

Noor, Tayyaba ^{[1
]}

Zubair, Atika ^{[1
]}

Bhatti, Mohammad Afzal ^{[1
]}

Waseem, Rizwan ^{[1
]}

机构：

[1] Ghurki Trust Teaching Hosp, Lahore Med & Dent Coll, Dept Paediat, Lahore, Pakistan

来源：

PAKISTAN JOURNAL OF MEDICAL & HEALTH SCIENCES | 2016年 / 10卷 / 01期

关键词：

Anti gliadin antibodies; Gluten-free diet; Celiac disease;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aim: Effects of gluten-free diet on immunological assays in children with celiac disease aging 2-15 years. Study design: Descriptive observational study. Setting: Department of Paediatric Ghurki Trust Teaching Hospital, Lahore. Sample size: 50 patients. Methodology: Total 50 cases were included. The immunological assays and proximal bowel biopsy were performed in every case. Results noted on proforma and analyzed. Results: Majority of biopsy proven cases responded to gluten free diet 80% and showed 73.3% improvement of anti gliadin (IgA) and 60.7% (IgG) while tissue transglutaminase IgA and IgG are improved in 85.3% after 4-6 months of treatment. Conclusion: There is gradual decline of titers of serum antigliadin and anti tissue transglutaminase. Patients with poor compliance to treatment were mostly early teenagers in whom disease remained unresolved

引用

页码：141 / 142

页数：2

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