AN IMPROVED SYNTHESIS OF N-ACETYLNEURAMINIC ACID

被引：22
作者：
HOW, MJ
HALFORD, MDA
STACEY, M
VICKERS, E
机构：
[1] Department of Chemistry, The University, Edgbaston
[2] Koch-Light Laboratories, Colnbrook,, Bucks Bucks
来源：
CARBOHYDRATE RESEARCH | 1969年 / 11卷 / 03期
关键词：
D O I：
10.1016/S0008-6215(00)80572-8
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The overall yield and stereoselectivity of the aldol condensation reactions of 2-acetamido-2-deoxy-D-glucose and 2-acetamido-2-deoxy-D-mannose with oxal-acetate at pH 10 are improved by the incorporation of borate ion in the reaction mixture. Borate ion inhibits the alkaline epimerisation of various 2-acylamino-2-deoxyaldoses. © 1969.
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页码：313 / &
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