SPIN TRAPPING STUDIES OF PHOTOCHEMICAL-REACTIONS

被引：20

作者：

CHIGNELL, CF

机构：

[1] Laboratory of Molecular Biophysics, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709

来源：

PURE AND APPLIED CHEMISTRY | 1990年 / 62卷 / 02期

关键词：

D O I：

10.1351/pac199062020301

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Spin trapping is a very useful technique to study the photochemistry of chemical photosensitizers that undergo electron or hydrogen-transfer (Type I) reactions upon UV or visible irradiation. The Type I photochemistry of chlorpromazine [2-chloro-N-(3-dimethylaminopropyl)-phenothiazine], 3,3‘ 4’ 5-tetrachlorosalicylanilide and 3, 4 ’, 5-tribromosalicylanilide has been investigated using 2-methyl-2-nitrosopropane (MNP) and 5, 5-dimethyl-1-pyrroline-N-oxide (DMPO) as spin traps. All compounds underwent dehalogenation upon UV-irradiation and the resultant aryl radicals were trapped and identified. © 1990 De Gruyter

引用

页码：301 / 305

页数：5

共 11 条

[1] FREE-RADICAL PRODUCTION BY CHLORPROMAZINE SULFOXIDE, AN ELECTRON-SPIN-RESONANCE SPIN-TRAPPING AND FLASH-PHOTOLYSIS STUDY [J].

BUETTNER, GR ;

MOTTEN, AG ;

HALL, RD ;

CHIGNELL, CF .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1986, 44 (01) :5-10

[2]

BUTTNER GR, 1989, PHOTOCHEM PHOTOBIOL, V49, P249

[3] PHOTOINDUCED FREE-RADICALS FROM CHLORPROMAZINE AND RELATED PHENOTHIAZINES - RELATIONSHIP TO PHENOTHIAZINE-INDUCED PHOTOSENSITIZATION [J].

CHIGNELL, CF ;

MOTTEN, AG ;

BUETTNER, GR .

ENVIRONMENTAL HEALTH PERSPECTIVES, 1985, 64 :103-110

[4]

DEVRIES H, 1981, PHARM WEEKBLAD SCI E, V3, P1570

[5] PHOTO-TOXICITY FROM EXOGENOUS AGENTS [J].

EMMETT, EA .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1979, 30 (04) :429-436

[6] SPIN TRAPPING [J].

JANZEN, EG .

ACCOUNTS OF CHEMICAL RESEARCH, 1971, 4 (01) :31-&

[7] PHOTOALLERGIC RESPONSES TO CHEMICALS [J].

KOCHEVAR, IE .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1979, 30 (04) :437-442

[8]

KOCHEVAR IE, 1981, J INVEST DERMATOL, V76, P59, DOI DOI 10.1111/1523-1747.EP12524886

[9] SPECTROSCOPIC STUDIES OF CUTANEOUS PHOTOSENSITIZING AGENTS .8. A SPIN-TRAPPING STUDY OF LIGHT-INDUCED FREE-RADICALS FROM CHLORPROMAZINE AND PROMAZINE [J].

MOTTEN, AG ;

BUETTNER, GR ;

CHIGNELL, CF .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1985, 42 (01) :9-15

[10]

PATHAK MA, 1969, BIOL EFFECTS ULTRAVI, P480

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