SYNTHESIS OF (+/-)-APHANORPHINE VIA AN AMINYLIUM ION INTERMEDIATE

被引：28

作者：

HONDA, T

YAMAMOTO, A

CUI, YS

TSUBUKI, M

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1992年 / 05期

关键词：

D O I：

10.1039/p19920000531

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A facile synthesis of (+/-)-aphanorphine 1 was achieved via the aminylium ion intermediate as a reactive species.

引用

页码：531 / 532

页数：2

共 8 条

[1] NEW METHODS FOR THE GENERATION OF EPISULFONIUM IONS - AN APPLICATION TO THE SYNTHESIS OF CARBOCYCLES VIA SULFENIUM ION PROMOTED ARENE ALKENE CYCLIZATIONS [J].

EDSTROM, ED ;

LIVINGHOUSE, T .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1986, 108 (06) :1334-1336

[2] APHANORPHINE, A NOVEL TRICYCLIC ALKALOID FROM THE BLUE-GREEN-ALGA APHANIZOMENON-FLOS-AQUAE [J].

GULAVITA, N ;

HORI, A ;

SHIMIZU, Y ;

LASZLO, P ;

CLARDY, J .

TETRAHEDRON LETTERS, 1988, 29 (35) :4381-4384

[3] STUDIES ON THE SYNTHESIS OF MORPHINAN AND ITS RELATED-COMPOUNDS - NEW ENTRY TO THE CONSTRUCTION OF BENZOMORPHAN RING SKELETON [J].

KAMETANI, T ;

NISHIMURA, M ;

SUZUKI, Y ;

HONDA, T .

HETEROCYCLES, 1986, 24 (07) :1791-1793

[4] SYNTHESIS OF A MORPHINAN FROM A BENZOCYCLOBUTENE DERIVATIVE - X-RAY STRUCTURE OF 3,3-ETHYLENEDIOXY-1,2,3,4,4A,10A-ALPHA-HEXAHYDRO-6,7-DIMETHOXYPHENANTHRENE-4A-BETA-CARBONITRILE [J].

KAMETANI, T ;

SUZUKI, Y ;

HONDA, T .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1986, (08) :1373-1377

[5] HOMOLYTIC CYCLIZATIONS OF N-CHLOROALKENYLAMINES [J].

STELLA, L .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1983, 22 (05) :337-350

[6] ENANTIOCONTROLLED SYNTHESIS OF (+)-APHANORPHINE FROM (R)-O-BENZYLGLYCIDOL - ASSIGNMENT OF ABSOLUTE-CONFIGURATION [J].

TAKANO, S ;

INOMATA, K ;

SATO, T ;

OGASAWARA, K .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1989, (21) :1591-1592

[7] THE ENANTIOSELECTIVE TOTAL SYNTHESIS OF NATURAL (-)-APHANORPHINE [J].

TAKANO, S ;

INOMATA, K ;

SATO, T ;

TAKAHASHI, M ;

OGASAWARA, K .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1990, (04) :290-292

[8] SILANE REDUCTIONS IN ACIDIC MEDIA .2. REDUCTIONS OF ARYL ALDEHYDES AND KETONES BY TRIALKYLSILANES IN TRIFLUOROACETIC ACID - SELECTIVE METHOD FOR CONVERTING CARBONYL GROUP TO METHYLENE [J].

WEST, CT ;

DONNELLY, SJ ;

KOOISTRA, DA ;

DOYLE, MP .

JOURNAL OF ORGANIC CHEMISTRY, 1973, 38 (15) :2675-2681

← 1 →