NATURE OF BIOLOGICAL ELECTRON-TRANSFER

被引：1674

作者：

MOSER, CC ^{[1
]}

KESKE, JM ^{[1
]}

WARNCKE, K ^{[1
]}

FARID, RS ^{[1
]}

DUTTON, PL ^{[1
]}

机构：

[1] UNIV PENN, DEPT BIOCHEM & BIOPHYS, JOHNSON RES FDN, PHILADELPHIA, PA 19104 USA

来源：

NATURE | 1992年 / 355卷 / 6363期

关键词：

D O I：

10.1038/355796a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Powerful first-order analysis of intraprotein electron transfer is developed from electron-transfer measurements both in biological and in chemical systems. A variation of 20 angstrom in the distance between donors and acceptors in protein changes the electron-transfer rate by 10(12)-fold. Protein presents a uniform electronic barrier to electron tunnelling and a uniform nuclear characteristic frequency, properties similar to an organic glass. Selection of distance, free energy and reorganization energy are sufficient to define rate and directional specificity of biological electron transfer, meeting physiological requirements in diverse systems.

引用

页码：796 / 802

页数：7

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