CLONING AND MOLECULAR CHARACTERIZATION OF THE MURINE HERPESVIRUS 68 GENOME

被引：177

作者：

EFSTATHIOU, S

HO, YM

MINSON, AC

机构：

[1] Division of Virology, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, Tennis Court Road

来源：

JOURNAL OF GENERAL VIROLOGY | 1990年 / 71卷

关键词：

D O I：

10.1099/0022-1317-71-6-1355

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Murine herpesvirus 68 (MHV-68) is a naturally occurring herpesvirus of small free-living rodents. In order to facilitate the molecular characterization of the virus genome, a library of cloned restriction fragments has been produced and restriction enzyme cleavage maps deduced for the enzymes BamHI, EcoRI and HindIII. The MHV-68 genome comprises a region of unique DNA of approximately 118 kbp which is flanked by variable numbers of a 1.23 kb repeat unit. The organization of the MHV-68 genome is, therefore, most similar to that of the lymphotropic γ2 group of herpesviruses which include herpesvirus saimiri and herpesvirus ateles.

引用

页码：1355 / 1364

页数：10

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