AUTOREGULATORY FACTORS OF SECONDARY METABOLISM AND MORPHOGENESIS IN ACTINOMYCETES

被引：53
作者：
HORINOUCHI, S
BEPPU, T
机构：
[1] University of Tokyo, Bunkyo-Ku, Tokyo
[2] Department of Agri-cultural Chemistry, University of Tokyo, Bunkyo-Ku, Tokyo
[3] The University of Tokyo, Bunkyo-Ku, Tokyo
[4] Department of Agricultural Chem-istry, The University of Tokyo, Bunkyo-Ku, Tokyo
来源：
CRITICAL REVIEWS IN BIOTECHNOLOGY | 1990年 / 10卷 / 03期
关键词：
D O I：
10.3109/07388559009038207
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The Gram-positive bacterial genus Streptomyces possesses interesting biological aspects, such as the ability to produce a wide variety of secondary metabolites and a mycelial form of growth that culminates in sporulation. A close relationship of secondary metabolism and cell differentiation has been well recognized; secondary metabolism might be a physiological expression of cell differentiation. A variety of diffusible low-molecular-weight chemical substances have been found to function in general as regulatory factors, like "hormones" in eukaryotes, for secondary metabolism and cell differentiation. Among these factors, A-factor has been most extensively studied. This review summarizes recent research on the chemical structures, functions, biosyntheses, and mode of action of these regulatory factors. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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页码：191 / 204
页数：14
相关论文
共 91 条
  • [21] GRAFE U, 1981, J ANTIBIOT, V34, P1385
  • [22] GRAFE U, 1985, FEMS MICROBIOL LETT, V28, P249
  • [23] INTERSPECIFIC INDUCERS OF CYTODIFFERENTIATION AND ANTHRACYCLINE BIOSYNTHESIS FROM STREPTOMYCES-BIKINENSIS AND STREPTOMYCES-CYANEOFUSCATUS
    GRAFE, U
    REINHARDT, G
    SCHADE, W
    ERITT, I
    FLECK, WF
    RADICS, L
    [J]. BIOTECHNOLOGY LETTERS, 1983, 5 (09) : 591 - 596
  • [24] A NEW INDUCER OF ANTHRACYCLINE BIOSYNTHESIS FROM STREPTOMYCES-VIRIDOCHROMOGENES
    GRAFE, U
    SCHADE, W
    ERITT, I
    FLECK, WF
    [J]. JOURNAL OF ANTIBIOTICS, 1982, 35 (12) : 1722 - 1723
  • [25] GRAFE U, 1986, REGULATION SECONDARY, P225
  • [26] GRUND AD, 1985, J GEN MICROBIOL, V131, P833
  • [27] MUTANTS BLOCKED IN STREPTOMYCIN PRODUCTION IN STREPTOMYCES-GRISEUS - THE ROLE OF A-FACTOR
    HARA, O
    BEPPU, T
    [J]. JOURNAL OF ANTIBIOTICS, 1982, 35 (03) : 349 - 358
  • [28] HARA O, 1983, J GEN MICROBIOL, V129, P2939
  • [29] INDUCTION OF STREPTOMYCIN-INACTIVATING ENZYME BY A-FACTOR IN STREPTOMYCES-GRISEUS
    HARA, O
    BEPPU, T
    [J]. JOURNAL OF ANTIBIOTICS, 1982, 35 (09) : 1208 - 1215
  • [30] HIGASHI A, 1989, ANN M JAPANESE SOC F, P98
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