AUTOREGULATORY FACTORS OF SECONDARY METABOLISM AND MORPHOGENESIS IN ACTINOMYCETES

被引:53
作者
HORINOUCHI, S
BEPPU, T
机构
[1] University of Tokyo, Bunkyo-Ku, Tokyo
[2] Department of Agri-cultural Chemistry, University of Tokyo, Bunkyo-Ku, Tokyo
[3] The University of Tokyo, Bunkyo-Ku, Tokyo
[4] Department of Agricultural Chem-istry, The University of Tokyo, Bunkyo-Ku, Tokyo
关键词
D O I
10.3109/07388559009038207
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The Gram-positive bacterial genus Streptomyces possesses interesting biological aspects, such as the ability to produce a wide variety of secondary metabolites and a mycelial form of growth that culminates in sporulation. A close relationship of secondary metabolism and cell differentiation has been well recognized; secondary metabolism might be a physiological expression of cell differentiation. A variety of diffusible low-molecular-weight chemical substances have been found to function in general as regulatory factors, like "hormones" in eukaryotes, for secondary metabolism and cell differentiation. Among these factors, A-factor has been most extensively studied. This review summarizes recent research on the chemical structures, functions, biosyntheses, and mode of action of these regulatory factors. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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页码:191 / 204
页数:14
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